Collision Primary Tumor of the Endometrium: Large Cell Neuroendocrine Carcinoma and Endometrioid Adenocarcinoma

• Wyatt Unger

  University of Arizona College of Medicine Department of Pathology, Department of Obstetrics and Gynecology, and Arizona Cancer Center, 1501 N. Campbell Avenue, #5205 Tucson, AZ 85724, USA

• Qian Tang

  University of Arizona College of Medicine Department of Pathology, Department of Obstetrics and Gynecology, and Arizona Cancer Center, 1501 N. Campbell Avenue, #5205 Tucson, AZ 85724, USA

• Danielle Summers

  University of Arizona College of Medicine Department of Pathology, Department of Obstetrics and Gynecology, and Arizona Cancer Center, 1501 N. Campbell Avenue, #5205 Tucson, AZ 85724, USA

• Wenxin Zheng

  University of Arizona College of Medicine Department of Pathology, Department of Obstetrics and Gynecology, and Arizona Cancer Center, 1501 N. Campbell Avenue, #5205 Tucson, AZ 85724, USA

This is the first reported case, to our knowledge, of a true collision primary tumor of the endometrium. Neuroendocrine carcinoma of the endometrium is itself a rare tumor. In this case we present a collision tumor of neuroendocrine carcinoma with endometrioid adenocarcinoma of the endometrium. The unique morphologic and immunophenotypic features of these tumors in this case are discussed, justifying the classification of this case as a collision primary tumor of the endometrium.

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