Biochemical Effect of Low-Level Radiation on Human Beings Examined by Directly Attached Radioactive Mineral

• Masao Takatori

  13-6, Yagami, Saiwai-ku, Kawasaki, Kanagawa, 212-0056, Japan

• Makoto Yagi

  7-18-3, Sasashita, Kohnan-ku, Yokohama, Kanagawa, 234-0053, Japan

Previously, we have reported the clinical significance of low-level radiation and also demonstrated the necessity to determine the threshold of radioactive levels in human beings. In the present study, apart from the direct exposure of alpha-ray with oral intake of radon222 dissolved water or inhaling radon222 gas, the experimental direct exposure to beta- and gamma-rays by wearing a cotton sack containing Samarskite with direct contact to skin for one month was conducted. The average of beta- and gamma-ray levels on the sack surface was approximately 400 μSV/hour. The biochemical laboratory tests involving immunological markers were assessed at the initial and end points. In this study, the partial but continual direct exposure of human body to beta- and gamma-rays for one month showed no harmful effects. There are no significant changes in any of the bio markers. Although this study is limited regarding the number of subjects, the procedure is quite simple; thus, the gathering data using this procedure by adjusting the types and levels of radioactivity would be helpful in finding out the accurate radioactive threshold in human beings.

Vaiserman A, Koliada A, Zabuga O, Socol Y. Health Impacts of Low-Dose Ionizing Radiation: Current Scientific Debates and Regulatory Issues. Dose-response: a publication of International Hormesis Society 2018; 16(3): 1559325818796331. https://doi.org/10.1177/1559325818796331

Feinendegen LE, Pollycove M. Biologic responses to low doses of ionizing radiation: detriment versus hormesis. 1. Dose responses of cells and tissues. J Nucl Med 2001; 42(7): 17N-27N.

Pollycove M, Feinendegen LE. Biologic responses to low doses of ionizing radiation: detriment versus hormesis. 2. Dose responses of organisms. J Nucl Med 2001; 42(9): 26N-37N.

Kondo S. Health effects of low level radiation. Madison, WI: Medical Physics 1993; 85-89.

Feinendegen LE, Loken MK, Booz J, Muhlensiepen H, Sondhaus CA, Bond VP. Cellular mechanisms of production and repair induced by radiation exposure and their consequences for cell system responses. Stem Cells 1995; 13(suppl 1): 7-20.

Pearce MS, Salotti JA, Little MP, McHugh K, Lee C, Kim KP, et al. Radiation exposure from CT scans in childhood and subsequent risk of leukemia and brain tumors: a retrospective cohort study. Lancet 2012; 380: 499-505. https://doi.org/10.1016/S0140-6736(12)60815-0

Doss M. Shifting the paradigm in radiation safety. Dose Response 2012; 10: 562-83. https://doi.org/10.2203/dose-response.11-056.Doss

Takatori M, Hattori S, Yagi M. Clinical significance of low dose radiation hormesis. Int J low Radiation 2010; 7: 511-19. https://doi.org/10.1504/IJLR.2010.037672

Takatori M, Yagi M, Hattori S. Potential solutions in radiation hormesis. J cancer Respdates 2013; 2: 95-98. https://doi.org/10.6000/1929-2279.2013.02.02.2

Takatori M, Takatori Y, Yagi M. Clinical significance of low-level radiation exposure om mammalian radiobiology investigated by radon (Rn222) dissolved water intake in a dog. J Can Res Updates 2016, 7: 134-137.

• PDF