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Anticancer Activity of Five Traditionally Used Medicinal Plants' Extracts

Authors

  • Ghazala H. Rizwani

    Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan

  • De-Shen Wang

    Department of Pharmaceutical Science, College of Pharmacy and Health Sciences, St. John’s University, Queen, UY, USA

  • Mansoor Ahmed

    Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan

  • Amir Hassan

    Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan

  • Zheng-Rong Lai

    Department of Pharmaceutical Science, College of Pharmacy and Health Sciences, St. John’s University, Queen, UY, USA

  • Affnan Zahid

    Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan

  • Najia Mansoor

    Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan

  • Huma Sharif

    Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan

  • Zhe-Sheng Chen

    Department of Pharmaceutical Science, College of Pharmacy and Health Sciences, St. John’s University, Queen, UY, USA

  • Zhi Shi

    Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, China

DOI:

https://doi.org/10.6000/1929-2279.2014.03.02.4

Keywords:

Operculina turpethum, EtOH extract, Cell line cytotoxic activity, MTT bioassay.

Abstract

 Natural products play a critical role in cancer prevention and therapy today. There are numbers of anticancer agents from natural products used in the clinic.Fighting cancers with novel natural products, especially those extracted from plants, is a potential strategy to develop new anticancer drugs..In the following study, various extracts of well known medicinal plants named Holoptelea integrifolia (F), Operculina turpethum (R), Cardiospermem halicacabum L (S), Dilonix regia (F), Sesbania grandifora seed have been studied for evaluating their anticancer activity. Our data showed that the cytotoxic activity of Operculina turpethum (R) ethanolic extractwas relative high for all 6 cancer cell lines as compared to other extracts. The active compound and anticancer mechanism of these extracts are worth investigating in the future.

References

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Published

2014-04-28

Issue

Vol. 3 No. 2 (2014)

Section

Articles

How to Cite

Anticancer Activity of Five Traditionally Used Medicinal Plants’ Extracts. (2014). Journal of Cancer Research Updates, 3(2),  103-107. https://doi.org/10.6000/1929-2279.2014.03.02.4

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