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Does Side Matter?: A Retrospective Study Exploring the Side Preference of Abnormal Hypermetabolic Adrenal Activity

Authors

  • Xueren Zhao

    Veterans Affairs Medical Center, Department of Radiology, Loma Linda, California, USA

  • Ohwook Kwon

    Loma Linda University Medical Center, Department of Radiology, Loma Linda, California, USA

  • Alex Yi

    Veterans Affairs Medical Center, Department of Radiology, Loma Linda, California, USA

  • Michael Staton

    Loma Linda University Medical Center, Department of Radiology, Loma Linda, California, USA

DOI:

https://doi.org/10.6000/1929-2279.2017.06.03.3

Keywords:

Adrenal, PET/CT, incidentaloma, F18-FDG.

Abstract

Hypermetabolic adrenal activity can be seen on F-18 FDG positron emission tomography (F-18 FDG PET) in
patients undergoing evaluation for malignancy. The adrenal glands are bilateral organs that are anatomically similar to
each other with no differences to arterial supply. They are also a common site of metastases. A retrospective study of
1135 patients with tumors at a veteran hospital was performed to see if hypermetabolic adrenal activity was more
common on the left or right. Chi-square analysis demonstrated a significant side preference, with hypermetabolic activity
occurring significantly more often in the left adrenal gland.

References

Chong S, Lee KS, Kim HY, Kim YK, Kim BT, Chung MJ, Yi CA and Kwon GY. Integrated PET-CT for the characterization of adrenal gland lesions in cancer patients: diagnostic efficacy and interpretation pitfalls. Radiographics 2006; 26: 1811-1824; discussion 1824-1816.

Mitty HA. Embryology, anatomy, and anomalies of the adrenal gland. Seminars in Roentgenology 1988; 23: 271-279.https://doi.org/10.1016/S0037-198X(88)80037-3

Tokiwa K, Nakamura K, Ogita S, Iwai N, Hagiwara A and Takahashi T. Lymphatic drainage of adrenal neuroblastoma. Journal of Pediatric Surgery 1993; 28: 927-929.https://doi.org/10.1016/0022-3468(93)90699-L

Wong KK, Arabi M, Bou-Assaly W, Marzola MC, Rubello D and Gross MD. Evaluation of incidentally discovered adrenal masses with PET and PET/CT. European journal of radiology 2012; 81: 441-450.https://doi.org/10.1016/j.ejrad.2010.12.060

Boland GW, Dwamena BA, Jagtiani Sangwaiya M, Goehler AG, Blake MA, Hahn PF, Scott JA and Kalra MK. Characterization of adrenal masses by using FDG PET: a systematic review and meta-analysis of diagnostic test performance. Radiology 2011; 259: 117-126.https://doi.org/10.1148/radiol.11100569

Blake MA, Singh A, Setty BN, Slattery J, Kalra M, Maher MM, Sahani DV, Fischman AJ and Mueller PR. Pearls and Pitfalls in Interpretation of Abdominal and Pelvic PET-CT 1. Radiographics 2006; 26: 1335-1353.https://doi.org/10.1148/rg.265055208

Jana S, Zhang T, Milstein DM, Isasi CR and Blaufox MD. FDG-PET and CT characterization of adrenal lesions in cancer patients. European journal of nuclear medicine and molecular imaging 2006; 33: 29-35.https://doi.org/10.1007/s00259-005-1915-8

Boland GWL, Blake MA, Holalkere NS and Hahn PF. PET/CT for the Characterization of Adrenal Masses in Patients with Cancer: Qualitative Versus Quantitative Accuracy in 150 Consecutive Patients. American Journal of Roentgenology 2009; 192: 956-962.https://doi.org/10.2214/AJR.08.1431

Vikram R, Yeung HD, Macapinlac HA and Iyer RB. Utility of PET/CT in differentiating benign from malignant adrenal nodules in patients with cancer. American Journal of Roentgenology 2008; 191: 1545-1551.https://doi.org/10.2214/AJR.07.3447

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Published

2017-08-12

Issue

Vol. 6 No. 3 (2017)

Section

Articles

How to Cite

Does Side Matter?: A Retrospective Study Exploring the Side Preference of Abnormal Hypermetabolic Adrenal Activity. (2017). Journal of Cancer Research Updates, 6(3), 70-73. https://doi.org/10.6000/1929-2279.2017.06.03.3

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