18F-FDG PET/CT Imaging in Detection of Intravascular Large B-Cell Lymphoma

• Fangyang Jiao

  PET Centre, Huashan Hospital, Fudan University, 518East Wuzhong Road, Shanghai, China

• Jingjie Ge

  Department of pathology, Huashan Hospital, FuDan University, 12Wulumuqi Road, Shanghai, China

• Zhongwen Zhou

  PET Centre, Huashan Hospital, Fudan University, 518East Wuzhong Road, Shanghai, China

• Yihui Guan

  PET Centre, Huashan Hospital, Fudan University, 518East Wuzhong Road, Shanghai, China

• Chuantao Zuo

  PET Centre, Huashan Hospital, Fudan University, 518East Wuzhong Road, Shanghai, China

 Intravascular large B-cell lymphoma (IVLBCL) is a rare type of extranodal large B-cell lymphoma. Now, it remains a diagnostic challenge, because of non-specific findings on clinical, laboratory, and imaging studies. Here we present a case of an IVLBCL patient, who presented with fever of unknown origin and had skin involvement, that ¹⁸F-FDG PET/CT showed increased metabolism on systemic subcutaneous fat layer with a SUVmax of 1.29. After five courses of R-CHOP, 18F-FDG PET/CT showed disappearance of the diffuse FDG accumulation on systemic subcutaneous fat layer with a SUVmax of 0.55. These features make this case unique.

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