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Successful Treatment, with Chemotherapy and Intravenous Administration of Ascorbic Acid, of a Patient with Peripheral T-Cell Lymphoma, Not Otherwise Specified

Authors

  • Chiaki Tokoro

    Palliative Care Team, Shinseikai Daiichi Hospital, Nagoya, Japan
    https://orcid.org/0009-0007-3277-1968

  • Atsushi Tashiro

    Palliative Care Team, Shinseikai Daiichi Hospital, Nagoya, Japan

  • Kenji Ina

    Palliative Care Team, Shinseikai Daiichi Hospital, Nagoya, Japan and Department of Geriatric Medicine, Shinseikai Daiichi Hospital, Nagoya, Japan
    https://orcid.org/0000-0001-8646-0611

  • Yoshiteru Tanaka

    Department of Pharmacy, Shinseikai Daiichi Hospital, Nagoya, Japan

  • Hiroyuki Kobayakawa

    Kobayakawa Clinic, Nagoya, Japan

  • Takashi Yoshida

    Department of Clinical Oncology, Nagoya Memorial Hospital, Nagoya, Japan
    https://orcid.org/0000-0002-1516-9613

  • Satoshi Kayukawa

    Department of Clinical Oncology, Nagoya Memorial Hospital, Nagoya, Japan
    https://orcid.org/0000-0002-9646-5114

DOI:

https://doi.org/10.30683/1929-2279.2024.13.01

Keywords:

Ascorbic acid, Peripheral T-cell lymphoma, Chemotherapy, Quality of life, EORTC QLQ-C30, Instrumental activities of daily living

Abstract

Here, we report the case of a 64-year-old man with peripheral T-cell lymphoma, not otherwise specified, who complained of diffuse lymphadenopathy and pancytopenia. This patient received the CHOP regimen followed by the CHP plus brentuximab vedotin regimen, and eventually experienced severe adverse effects, such as leukocytopenia and thrombocytopenia. He was then intravenously administered high doses of ascorbic acid to enhance the effects of chemotherapy drugs and reduce the intensity of the side effects. Positron emission tomography-computed tomography revealed a complete response of the lesions to combination therapy. This case report demonstrated the feasibility, efficacy, and acceptable toxicity of high-dose ascorbic acid in patients undergoing chemotherapy.

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Published

2024-02-13

Issue

Vol. 13 (2024)

Section

Articles

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How to Cite

Successful Treatment, with Chemotherapy and Intravenous Administration of Ascorbic Acid, of a Patient with Peripheral T-Cell Lymphoma, Not Otherwise Specified. (2024). Journal of Cancer Research Updates, 13, 1-5. https://doi.org/10.30683/1929-2279.2024.13.01

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