Magnetotherapy in Experimental and Clinical Neuro-Oncology: A Review


  • F.F. Borichevsky Department of Neurology, Minsk Central Regional Clinical Hospital, Borovlyani, Republic of Belarus
  • I.S. Lioubichtchev Department of Neurosurgery, Minsk Regional Clinical Hospital, Lesnoy, Republic of Belarus
  • A.E. Sahun Department of Neurosurgery, Minsk Regional Clinical Hospital, Lesnoy, Republic of Belarus
  • A.S. Trus Department of Neurosurgery, Minsk Regional Clinical Hospital, Lesnoy, Republic of Belarus
  • D.A. Tzerkovsky Laboratory of Morphology, Molecular and Cellular Biology with Group of Experimental Medicine, N.N. Alexandrov National Cancer Center of Belarus, Lesnoy, Republic of Belarus



Neuro-oncology, malignant brain tumors, treatment, magnetotherapy


The purpose of this publication is not to state the fact of the high antitumor effectiveness of the gold standard treatment of malignant brain tumors (surgical intervention with adjuvant chemoradiotherapy), but to consider the possibility of using alternative therapeutic options, in particular, magnetotherapy, as a component of the treatment of patients with this serious pathology, as well as a method of preventing a number of postoperative adverse reactions.


Khan S, El Kouatly M, Kambris ET, et al. Epidemiology of brain tumors in the United Arab Emirates: a national registry cross sectional study. BMC Neurology 2020; 20: 301. DOI:

GBD 2016 Brain and Other CNS Cancer Collaborators. Global, regional, and national burden of brain and other CNS cancer, 1990 – 2016: a systematic analysis for the global burden of disease study 2016. Lancet Neurol 2019; 18: 376-93. DOI:

Chang SM, Parney IF, Huang W, et al. Patterns of care for adults with newly diagnosed malignant glioma. JAMA 2005; 293: 557-64. DOI:

Pouchieu С, Gruber A, Berteaud E, et al. Increasing incidence of central nervous system (CNS) tumors (2000-2012): findings from a population based registry in Gironde (France). BMC Cancer 2018; 18(1): 1-13. DOI:

Omuro A, DeAngelis LM. Glioblastoma and other malignant gliomas. A clinical review. JAMA 2013; 310(17): 1842-50. DOI:

Nieder C, Grosu AL, Molls M. A comparison of treatment results for recurrent malignant gliomas. Cancer Treat Rev 2000; 26: 397-409. DOI:

Lacroix M, Abi-Said D, Fourney DR, et al. A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg 2001; 95(2): 190-98. DOI:

Tserkovsky DA. Photodynamic therapy of malignant brain tumors: the current state of the problem. Oncol J 2011; 5(1): 129-38 (in Russian).

Roth P, Gramatzki D, Weller M. Management of elderly patients with glioblastoma. Curr Neurol Neurosci Rep 2017; 17(4): 1-22. DOI:

Yousuf A, Oliva CR, Noman ASM, et al. Radioresistance in glioblastoma and the development of radiosensitizers. Cancers (Basel) 2020; 12(9): 2511. DOI:

Pletnev AS, Ulashchik VS. Magnetic fields in experimental and clinical oncology. Minsk: Belorusskaya navuka, 2016; p. 229 (in Russian).

Magnetotherapy: theoretical foundations and practical application. under the general editorship of Prof. V.S. Ulashchik. Minsk. 2015; p. 379 (in Russian).

Akbarnejad Z, Eskandary H, Vergallo C, et al. Effects of extremely low-frequency pulsed electromagnetic field on glioblastoma cells (U87). Electromagn Biol Med 2017; 36(3): 238-47. DOI:

Akbarnejad Z, Eskandary H, Dini L, et al. Cytotoxicity of temozolomide on human glioblastoma cells is enhanced by the concomitant exposure to an extremely low-frequency electromagnetic field (100Hz, 100G). Biomed Pharmacother 2017; 92: 254-64. DOI:

Atmachidi DP. Adjuvant chemoradiotherapy with the use of a magnetic field in the complex treatment of malignant glial brain tumors: abstract. dis. Candidate of Medical Sciences. Rostov on Don, 2009; p. 27 (in Russian).

Popov IA, Shixliarova AI, Rostorguev EE, et al. Inhibitory effect of pulsed magnetic fields and ionizing radiation on human glioblastoma cell culture T98G. Med Bull North Caucasus 2019; 14(1.2): 228-31 (in Russian). DOI:

Sidorenko YuS, Kit OI, Popov IA, et al. The influence of pulsed magnetic fields on the expression of oncosuppressor genes in an experiment on human glioblastoma cell culture T98G. Siber Oncol J 2019; 18(6): 57-66 (in Russian). DOI:

Popov IA, Sidorenko YuS, Kit OI, et al. The use of pulsed transcranial magnetic stimulation (TMS) at the stages of complex treatment of patients with malignant gliomas of the brain. Neuroscience for medicine and psychology: XVI International Interdisciplinary Congress. Sudak, Crimea, Russia; October 6–16, 2020 Proceedings of the Congress. Edited by Loseva EV, Kryuchkova AV, Loginova NA. Moscow: MAKS Press. 2020; p. 380 (in Russian). DOI:

Popov IA. The use of transcranial electromagnetotherapy in the complex treatment of patients with malignant glial tumors of the brain: abstract. dis. Candidate of Medical Sciences. Rostov on Don, 2021; p. 26 (in Russian).




How to Cite

Borichevsky, F., Lioubichtchev, I., Sahun, A., Trus, A., & Tzerkovsky, D. (2023). Magnetotherapy in Experimental and Clinical Neuro-Oncology: A Review. Journal of Analytical Oncology, 12, 72–76.