Twice Operations for Parotid Metastasis of Nasopharyngeal Carcinoma Patient after Radical Intensity-Modulated Radiotherapy: A Case Report
- Authors
-
-
Guangmou Tan
Department of Head and Neck Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, China -
Weiquan Chen
Department of Head and Neck Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, China -
Xiaojun Tan
Department of Pathology, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, China -
Haiyan Huang
Department of Head and Neck Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, China -
Ke Liu
Department of Head and Neck Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, China -
Hong Yang
Department of Head and Neck Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, China
-
- Keywords:
- Nasopharyngeal carcinoma, Parotid lymph node metastasis, Prognosis, Intensity-modulated radiotherapy, Surgery.
- Abstract
-
The surgery treatment of parotid metastasis of nasopharyngeal carcinoma (NPC) after parotid-gland-sparing IMRT is rare report. We present such a case of NPC patient cT2N2M0 with parotid lymph node metastasis after parotid-gland-sparing IMRT patient who accepted the second operation after the first failure parotid section. This case reminded us that neck dissection added the whole parotid gland resection may be an appropriate method to treat this type of patients.
- Downloads
-
Download data is not yet available.
- References
-
Wei WI, Sham JS. Nasopharyngeal carcinoma. The Lancet 2005; 365: 2041-54. https://doi.org/10.1016/S0140-6736(05)66698-6
Lee AW, Ma BB, Ng WT, Chan AT. Management of Nasopharyngeal Carcinoma: Current Practice and Future Perspective. J Clin Oncol 2015; 33: 3356-64. https://doi.org/10.1200/JCO.2015.60.9347
Ho FC, Tham IW, Earnest A, Lee KM, Lu JJ. Patterns of regional lymph node metastasis of nasopharyngeal carcinoma: a meta-analysis of clinical evidence. BMC Cancer 2012; 12: 98. https://doi.org/10.1186/1471-2407-12-98
Wang X, Hu C, Ying H, et al. Patterns of lymph node metastasis from nasopharyngeal carcinoma based on the 2013 updated consensus guidelines for neck node levels. Radiol Oncol 2015; 115: 41-45. https://doi.org/10.1016/j.radonc.2015.02.017
Peng G, Wang T, Yang KY, et al. A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma. Radiother Oncol 2012; 104: 286-93. https://doi.org/10.1016/j.radonc.2012.08.013
Nutting CM, Morden JP, Harrington KJ, et al. Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial. The Lancet Oncology 2011; 12: 127-36. https://doi.org/10.1016/S1470-2045(10)70290-4
Cannon DM, Lee NY. Recurrence in region of spared parotid gland after definitive intensity-modulated radiotherapy for head and neck cancer. Int J Radiat Oncol Biol 2008; 70: 660. https://doi.org/10.1016/j.ijrobp.2007.09.018
Cao CN, Luo JW, Gao L, Xu GZ, Li SY, Xiao JP. Recurrence of nasopharyngeal carcinoma in the parotid region after definitive intensity-modulated radiotherapy. J Oral Maxillofac Surg 2013; 71: 1993-7. https://doi.org/10.1016/j.joms.2013.04.002
Lin DS, Jen YM, Lee JC, Liu SC, Lin YS. Recurrence of nasopharyngeal carcinoma in the parotid region after parotid-gland-sparing radiotherapy. J Formos Med Assoc 2011; 110: 655-66. https://doi.org/10.1016/j.jfma.2011.08.009
Grégoire V, Ang K, Budach W, et al. Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines. Radiother Oncol 2014; 110: 172-181. https://doi.org/10.1016/j.radonc.2013.10.010
Olsen SM, Moore EJ, Koch CA, Kasperbauer JL, Olsen KD. Oral cavity and oropharynx squamous cell carcinoma with metastasis to the parotid lymph nodes. Oral oncology 2011; 47: 142-4. https://doi.org/10.1016/j.oraloncology.2010.11.010
Xu Y, Chen X, Zhang M, et al. Prognostic effect of parotid area lymph node metastases after preliminary diagnosis ofnasopharyngeal carcinoma: propensity score matching study. Cancer Med 2017; 6:2213-21. https://doi.org/10.1002/cam4.1154
Wang HZ, Cao CN, Luo JW, et al. High-risk factors of parotid lymph node metastasis in nasopharyngeal carcinoma: a case-control study. Radiat Oncol 2016; 11: 113. https://doi.org/10.1186/s13014-016-0691-x
Cao CN, Luo JW, Gao L, et al. Clinical characteristics and patterns of failure in the parotid region after intensity-modulated radiotherapy for nasopharyngeal carcinoma. Oral Oncology 2013; 49: 611-4. https://doi.org/10.1016/j.oraloncology.2013.02.001
- Downloads
- Published
- 13-08-2017
- Issue
- Vol. 6 No. 4 (2017)
- Section
- Articles
How to Cite
Similar Articles
- Wenying Zhang, Hui Di, Renpei Xia, Jiali Yang, Junfeng Zhang, Jianyou Gu, PSMD14 Drives Clear Cell Renal Cell Carcinoma Progression via JAK/STAT3 Signaling , Journal of Cancer Research Updates: Vol. 15 No. 1 (2026)
- Asma Kassab, Awatef Msolly, Abdelhedi Miled, Olfa Gharbi, Alpha-Fetoprotein Producing Breast Cancer Cells: Case Report and Review of Literature , Journal of Cancer Research Updates: Vol. 2 No. 3 (2013)
- Brianna N. Harris, Uttam K. Sinha, Cancer Stem Cells: A Review of the Literature and the Implications in Head and Neck Cancer , Journal of Cancer Research Updates: Vol. 2 No. 3 (2013)
- Janet Wangari-Talbot, Elizabeth Hopper-Borge, Drug Resistance Mechanisms in Non-Small Cell Lung Carcinoma , Journal of Cancer Research Updates: Vol. 2 No. 4 (2013)
- Dhafer A. Alghezi, Rasha Aljawher, Hameed Naeem Mosa, Increased KI67 Immunostaining is Associated with Breast Cancer Aggressiveness , Journal of Cancer Research Updates: Vol. 14 (2025)
- Leonello Tacconi, Gennaro D’Acunzi, Camilla Russo, Andrea Manto, Ginevra F. D’Onofrio, Raffaele Fristachi, About a Rare Case of Low-Grade Chondrosarcoma of the Cranial Vault , Journal of Cancer Research Updates: Vol. 7 No. 1 (2018)
- Sh.R. Kzyrgalin, K.Sh. Gantsev, A.A. Rizvanov, Sh.Kh. Gantsev, New Insight of Oncology: Cancer Concept without Tumor , Journal of Cancer Research Updates: Vol. 13 (2024)
- Erkin Bilalov, Dilshodjon Usarov, Turabek Boyqulov, Marhabo Matniyozova, Mohamed Hisham, Neetish Kumar, Deep Learning Guided Radiogenomic Signatures for Prognostic Stratification in Glioblastoma Multiforme , Journal of Cancer Research Updates: Vol. 14 (2025)
- Zahraa A.G. AL Ghuraibawi, Mohammed Mahmood Kamil, Khaleel Ibraheem Mohson, Zainab Ghazi Sadeq, Mareym M. Alkhaiat, Hematological Parameters in Liver Metastasis: A Comprehensive Clinical Evaluation for Early Detection in Iraqi Patients , Journal of Cancer Research Updates: Vol. 14 (2025)
- Zahraa A.G. Al Ghuraibawi, Evaluation of Interleukin-8 (IL-8) Levels before and after Radiotherapy in Thyroid Carcinoma Patients , Journal of Cancer Research Updates: Vol. 14 (2025)
You may also start an advanced similarity search for this article.